儿童癌症中的血栓性并发症
Alkistis Adramerina1, Marina Economou1
11st Pediatric Department, Faculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, 54250 Thessaloniki, Greece.
Children (Basel, Switzerland)
|September 28, 2024
概括
儿童癌症患者经常经历血栓栓塞 (TE),受癌症类型,治疗和遗传因素的影响. 为了在患有癌症的儿童中制定有效的预防和管理策略,需要进一步的研究.
科学领域:
- 在瘤学瘤学.
- 血液学 血液学 血液学
- 儿科 儿科 儿科
背景情况:
- 血栓栓塞栓症 (TE) 是儿科癌症患者的重大并发症.
- 风险因素包括年龄,血型,癌症类型/部位,遗传性血栓性,中央静脉导管和化疗.
研究的目的:
- 审查当前对儿童癌症相关TE的理解.
- 突出基于证据的指导方针和进一步研究的需要.
主要方法:
- 关于儿童瘤学中TE风险因素,管理和预防的文献综述.
- 对当前治疗限制和潜在替代方案的分析.
主要成果:
- 在儿童癌症患者中,TE通常会影响四肢.
- 目前的管理依赖于一般的儿科TE指南,因为缺乏特定的儿科瘤学协议.
- 直接口服抗凝剂显示出潜力,但需要在这个人群中进行进一步的安全性和有效性研究.
结论:
- 与癌症相关的TE仍然是儿科瘤学中致病率的重要原因.
- 迫切需要大型多中心试验,以制定TE治疗和癌症儿童血栓预防的指导方针.
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