针对炎症和癌症治疗的免疫调节性半孔纳米颗粒的进展

Bin Gu1, Qin Zhao1, Yiran Ao1

  • 1State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Bio-Medicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China.

Biomolecules
|September 28, 2024
PubMed
概括

半孔纳米粒子 (MSNs) 通过改善抗原呈现和减少副作用,显示出作为癌症免疫疗法的载体的希望. 对它们的免疫调节机制的进一步研究可以促进新型免疫疗法的开发.

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Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
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