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Updated: Jun 11, 2025

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在人类巨细胞激活中,马力酶1的转录调节和功能

Anna Santarsiero1, Simona Todisco1, Paolo Convertini1

  • 1Department of Science, University of Basilicata, 85100 Potenza, Italy.

Biomedicines
|September 28, 2024
PubMed
概括

酶1 (ME1) 在激活的巨细胞中被上调,并由NF-κB控制. 抑制ME1降低了炎症媒介,为免疫代谢调节提供了一个目标.

关键词:
在 NF-κBB 中.在PGE2的基础上,PGE2基因表达的基因表达方式免疫代谢的免疫代谢.这是一种炎症炎症炎症炎症.巨细胞激活活动马利克酶 1 马利克酶 1氧化氧化的使用方法有活性氧物种的反应性氧物种.

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Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a  complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
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