标准化葡萄 (Vitis vinifera L.) 提取物改善健康老年人的短期和长期认知表现:一个随机,双盲和安慰剂控制的试验
Fabio Amone1, Amelia Spina1, Anna Perri2
1R&D Department, Nutratech S.r.l., 87036 Rende, CS, Italy.
Foods (Basel, Switzerland)
|September 28, 2024
概括
每天服用葡萄汁提取物 (Cognigrape®) 在14天内显著改善了健康老年人的记忆和注意力等认知功能. 这种天然补充剂显示了增强认知健康和寿命的潜力.
科学领域:
- 神经科学和衰老研究研究
- 营养神经科学 营养神经科学
- 老年学是一门学科.
背景情况:
- 认知能力下降是衰老的一个常见方面,影响日常生活和独立.
- 与年龄相关的认知障碍会影响记忆,处理速度,语言和执行功能.
研究的目的:
- 评估标准化葡萄汁提取物 (Cognigrape®) 在改善健康老年人的认知功能方面的疗效.
- 评估葡萄提取物对认知的短期 (急性) 和长期 (慢性) 影响.
主要方法:
- 一个双盲,安慰剂控制的临床试验,涉及96名健康的老年人.
- 参与者每天服用250毫克的Cognigrape® (Vitis vinifera L. 果汁提取物).
- 用标准化测试评估认知功能,包括MMSE,RBANS,ENB-2和MBT.
主要成果:
- 观察到在即时和延迟记忆,视觉空间能力,语言和注意力方面的显著改善.
- 认知能力的提高在14天内就显而易见,并在补充剂服用84天后继续改善.
- 选择性注意力显示,仅在第一剂后90分钟,显著改善.
结论:
- 葡萄汁提取物 (Cognigrape®) 在改善健康老年人的认知功能方面表现出有效性.
- 提取物为认知健康提供了急性和慢性益处,支持更长的健康寿命.
- 来自Vitis vinifera L.的天然化合物显示出作为减轻与年龄相关的认知衰退的战略具有前途.
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