甲状腺体积和功能的关系与脚-手腕指数,脚-手腕指数和脚压力在18-65岁甲状腺患者中的关系
Grzegorz K Jakubiak1, Natalia Pawlas1, Małgorzata Morawiecka-Pietrzak2
1Department of Pharmacology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 41-800 Zabrze, Poland.
Medicina (Kaunas, Lithuania)
|September 28, 2024
概括
即使在没有甲状腺疾病的轻甲状腺患者中,甲状腺激素和甲状腺体积也与亚临床心血管功能障碍相关,特别是脚-手腕指数 (ABI) 和脚-手腕指数 (TBI). 这表明甲状腺状况和心血管问题的早期迹象之间存在联系.
科学领域:
- 内分泌学 在内分泌学.
- 心脏病学 心脏病学
- 血管生物学 血管生物学
背景情况:
- 甲状腺功能与心血管健康之间的关系已经得到了很好的证实.
- 然而,甲状腺激素和亚临床心血管功能障碍在平甲状腺患者之间的关联仍然不清楚.
- 亚临床功能障碍可以使用诸如脚-手臂指数 (ABI) 和脚-手臂指数 (TBI) 等措施来评估.
研究的目的:
- 调查甲状腺功能参数 (甲状腺激素[TSH],自由甲状腺素[FT4],自由三甲状腺素[FT3]),甲状腺体积 (TV) 和亚临床心血管功能障碍标志物 (ABI,TBI) 之间的关联.
- 为了探索在没有被诊断为甲状腺疾病的个体中的相关性.
主要方法:
- 一项涉及45名没有甲状腺疾病的euthyroid参与者的研究.
- 方法包括甲状腺超声波,生物化学甲状腺功能测试,以及ABI和TBI的测量.
- 没有包括急性疾病或健康恶化的参与者.
主要成果:
- 在FT3和ABI和TBI的参数之间观察到显著的相关性.
- TSH与最大TBI有显著的相关性,而FT4与最小TBI有显著的相关性.
- 甲状腺体积 (TV) 与脚压 (TP) 和TBI参数相关,但没有ABI.
结论:
- 甲状腺体体积和功能与亚临床心血管功能障碍 (ABI,TBI) 之间存在显著的相关性,即使在没有被诊断为甲状腺疾病的人中也是如此.
- 这些发现强调了甲状腺状况和早期血管变化之间的潜在联系.
- 需要进一步的研究来阐明这些关联的临床影响.
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