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哈西莫托甲状腺炎患者的饮食炎症指数和甲状腺功能的关联:观察性跨部门多中心研究
Sanja Klobučar1,2, Gordana Kenđel Jovanović3, Jadwiga Kryczyk-Kozioł4
1Department of Endocrinology, Diabetes and Metabolic Diseases, Clinical Hospital Centre Rijeka, 51000 Rijeka, Croatia.
Medicina (Kaunas, Lithuania)
|September 28, 2024
概括
抗炎饮食可能有利于患有哈西莫托甲状腺炎 (HT) 的个体. 通过饮食变化降低饮食炎症指数 (DII) 得分可以改善HT患者的健康结果.
科学领域:
- 内分泌学 在内分泌学.
- 营养科学 营养科学
- 免疫学 免疫学 免疫学
背景情况:
- 具有高炎症潜力的饮食模式,以高的饮食炎症指数 (DII) 评分来表示,与炎症有关,并可能影响甲状腺功能.
- 哈西莫托甲状腺炎 (HT) 是一种影响甲状腺的自身免疫性疾病,在甲状腺中,炎症起着关键作用.
研究的目的:
- 为了研究饮食炎症潜力 (DII评分) 和大人的甲状腺功能之间的关联 哈西莫托的甲状腺炎.
- 探索DII,甲状腺激素 (TSH,FT4),甲状腺抗体 (TPO-Ab) 和炎症标志物 (hsCRP) 之间的关系.
主要方法:
- 观测性,横截面,多中心研究,涉及149名被诊断患有HT的成年人.
- 饮食炎症指数 (DII) 是使用141项食物频率问卷 (FFQ) 计算的.
- 测量了TSH,ft4,TPO-Ab和hsCRP的血清水平.
主要成果:
- 具有更多抗炎饮食 (较低的DII) 的参与者具有显著更高的自由甲状腺素 (fT4) 水平.
- 在DII得分和TSH水平之间观察到显著的正相关性 (p < 0.001).
- 在DII得分和FT4水平 (p < 0.001) 之间也发现了显著的正相关性,在调整后仍然存在.
结论:
- 坚持抗炎饮食似乎对患有哈西莫托甲状腺炎的患者有益.
- 改变饮食以降低DII得分可能是改善HT患者临床结果的有价值策略.
- 对管理HT的饮食干预措施的进一步研究是有必要的.
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