自我报告的与NSAID和咖啡因消费相关的胃肠道症状在约旦亚群中
Sofian Al Shboul1, Omar Maloul1, Hamza Al-Trad1
1Department of Pharmacology and Public Health, Faculty of Medicine, The Hashemite University, Zarqa 13133, Jordan.
Medicina (Kaunas, Lithuania)
|September 28, 2024
概括
非类固醇抗炎药物 (NSAID) 和咖啡因消费与胃肠道 (GI) 症状增加有关,包括胃潰瘍疾病 (PUD). 这项研究强调了需要安全使用指南,以减少胃肠道疾病的患病率.
科学领域:
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 非类固醇抗炎药物 (NSAID) 和含咖啡因的饮料在全球范围内被广泛使用.
- 它们对胃肠道 (GI) 健康的综合影响需要进一步研究,特别是在多种不同的人群中.
研究的目的:
- 调查NSAID使用,咖啡因饮料消费和自我报告的胃肠道症状之间的关联.
- 为了确定与胃潰瘍疾病 (PUD) 相关的胃肠道症状在约旦亚种群中的患病率.
主要方法:
- 在400名约旦成年人 (18-65岁) 中进行了一项横截面在线调查.
- 收集的数据包括社会人口统计,NSAID使用,咖啡因摄入量,PUD病史和胃肠道症状.
- 统计分析包括应急表来计算赔率比率 (OR) 和95%置信区间 (CI).
主要成果:
- 自我报告的PUD相关的GI症状的患病率为6.0%.
- 无 NSAID 用户的PUD,腹痛和不适的几率明显更高.
- 咖啡因消费与燃烧的胃疼痛,腹和膨胀的可能性增加有关.
结论:
- 使用NSAID和摄入咖啡因独立地与自我报告的PUD和相关的胃肠道症状的更高患病率有关.
- 这些发现强调了考虑NSAIDs和咖啡因对胃肠道的影响的重要性.
- 公共卫生战略应促进这些常见物质的安全使用,以减轻胃肠道疾病的负担.
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