隔离夜间掩盖的患病率和特征 在治疗患者中不受控制的高血压
Kang Hee Kim1, Jaehoon Chung1, Suyoung Jang1
1Department of Cardiology, Dongguk University Ilsan Hospital, Goyang-si 10326, Gyeonggi-do, Republic of Korea.
Medicina (Kaunas, Lithuania)
|September 28, 2024
概括
隔离性夜间掩盖的失控高血压 (IN-MUCH) 影响了近35%的治疗患者,通常是正常的办公室血压. 这种情况给高血压管理带来了独特的挑战,需要进一步研究.
科学领域:
- 心脏病学 心脏病学
- 高血压研究 高血压研究
- 临床试验 临床试验
背景情况:
- 蒙面的失控高血压带来了诊断挑战,特别是当它仅在晚上发生时.
- 了解隔离夜间蒙面无控制高血压 (IN-MUCH) 的患病率和特征对于有效的患者管理至关重要.
研究的目的:
- 评估在接受抗高血压治疗的患者中IN-MUCH的患病率和特征.
- 将IN-MUCH与其他高血压表型进行比较,包括受控高血压 (CH).
主要方法:
- 一项涉及701名20岁以上接受抗高血压药物治疗的参与者的研究.
- 利用三天的办公室血压 (BP) 和24小时的门诊BP监测进行分类.
- 高血压的表型包括CH,隔离的白天掩盖的不受控制的高血压 (ID-MUCH),IN-MUCH以及白天和夜间掩盖的不受控制的高血压 (DN-MUCH).
主要成果:
- 在544名具有有效数据和受控办公室BP的参与者中,IN-MUCH在34.9%的参与者中流行.
- 与CH相比,IN-MUCH在男性和饮酒者中更为常见.
- 患有IN-MUCH的患者比CH患者有更高的静脉血压 (SBP) 和静脉血压 (DBP) 的办公室.
- 在IN-MUCH的患病率因办公室BP而异:37.6% (最佳),38.5% (正常) 和27.9% (高正常).
- 在IN-MUCH患者中,51.6%有孤立的不受控制的DBP,41.1%有不受控制的SBP和DBP.
- 年龄较小,男性性别和酒精消费与孤立的不受控制的DBP有关.
结论:
- IN-MUCH明显流行,特别是在正常或最佳办公室血压患者中,表明需要量身定制的治疗策略.
- 需要进行进一步的研究,以确定在IN-MUCH的预后中是否需要区分单独的不受控制的DBP和联合的SBP/DBP.
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