血小板病原体减少技术-我们应该留下还是我们应该去...?
Andrea Piccin1,2,3, Allameddine Allameddine1, Gilbert Spizzo4
1Northern Ireland Blood Transfusion Service (NIBTS), Belfast BT9 7TS, UK.
Journal of clinical medicine
|September 28, 2024
概括
病原体减少技术 (PRT) 为输血服务 (BTS) 提供了一个有前途的解决方案,以减轻输血传播感染 (TTI) 和供应短缺的风险,特别是在COVID-19大流行后. 需要对血小板PRT进行进一步评估,以评估其成本效益和整合到标准护理中.
科学领域:
- 血液输血 医学 输血 医学
- 传染病控制和控制传染病
- 公共卫生 公共卫生
背景情况:
- COVID-19大流行凸显了输血服务 (BTS) 的脆弱性,影响了血液产品的可用性和安全性.
- 全球旅行和全球化导致捐赠者池减少,并提高了对输血传播感染 (TTI) 的认识.
- 病原体减少技术 (PRT) 已成为提高血液安全性和供应弹性的一种潜在工具.
研究的目的:
- 在输血服务 (BTS) 中对血小板产品实施病原体减少技术 (PRT) 的作用和挑战进行批判性评估.
- 讨论PRT采用对BTS手术和血液供应的影响.
- 分析将PRT整合到标准输血实践中的成本效益.
主要方法:
- 基于现有文献和专家意见的批判性评论.
- 审查验证PRT用于输血传播感染 (TTI) 控制的研究.
- 讨论PRT实施的运营挑战和经济考虑.
主要成果:
- PRT已被验证用于控制输血传染性感染 (TTI),但尚未成为许多输血服务 (BTS) 的标准护理.
- 对血小板进行PRT的实施给BTS带来了特殊的挑战.
- 采用PRT的成本效益需要仔细考虑.
结论:
- PRT具有显著的潜力,可以提高血液安全性并减轻输血服务 (BTS) 的风险,特别是在全球卫生挑战的背景下.
- 解决挑战和评估成本效益对于PRT的广泛采用至关重要.
- 需要进一步的研究和战略规划,以有效地将PRT纳入常规输血实践中.
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