心房与快速心室反应对心房复发的影响:来自CODE-AF注册表
Joo Hee Jeong1, Yong-Soo Baek2, Junbeom Park3
1Division of Cardiology, Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul 02841, Republic of Korea.
Journal of clinical medicine
|September 28, 2024
概括
患有心房 (AF) 和快速心室反应 (RVR) 的患者的AF复发率较低. 在AF患者中,RVR是早期节律控制的有利标志物,而不会增加主要的心血管不良事件.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
背景情况:
- 快速心室反应 (RVR) 和心房 (AF) 复发之间的关联尚未得到充分证实.
- 调查RVR对AF复发的影响对于了解AF管理至关重要.
研究的目的:
- 为了确定RVR对心房动 (AF) 复发的影响.
- 评估AF患者的RVR和主要心血管不良事件 (MACE) 之间的关系.
主要方法:
- 分析了非膜AF患者的前性多中心注册表.
- RVR被定义为AF,心室速率大于110bpm.
- AF复发和MACE分别是主要和次要终点,平均随访时间为28.6个月.
主要成果:
- 在5533名患者中,8.9%的人有RVR. 患有RVR的患者年轻,并且更频繁地患有阳性AF.
- RVR组的AF复发率显著降低 (HR:0.58,p <0.001).RVR组的AF复发率显著降低 (HR:0.58,p <0.001).RVR组的AF复发率显著降低 (HR:0.58,p <0.001).
- 在RVR和非RVR组之间没有观察到MACE的显著差异 (HR:0.96,p = 0.800). 有RVR的AF独立预测了较低的AF复发.
结论:
- 在心房患者中,快速心室反应与显著降低AF复发相关.
- RVR是AF的有利预后标志物,表明早期节律控制策略可能有好处.
- 在AF患者中,RVR似乎不会增加主要心血管不良事件的风险.
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