在单子妊娠中带插入的风险因素-系统性审查和元分析
Antonios Siargkas1, Ioannis Tsakiridis1, Athanasios Gatsis1
1Third Department of Obstetrics and Gynecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Agiou Dimitriou, 54124 Thessaloniki, Greece.
Journal of clinical medicine
|September 28, 2024
概括
这项元分析发现,辅助生殖技术,无双性,吸烟和胎盘前置是带插入 (VCI) 的重要危险因素. 了解这些因素可以改善单子妊娠中VCI的产前鉴定.
科学领域:
- 产科和妇科 产科和妇科
- 围产儿医学 围产儿医学
- 生殖健康 生殖健康
背景情况:
- 带插入 (VCI) 是一种异常,带插入胎儿膜而不是胎盘.
- 准确的产前识别VCI对于管理潜在的并发症至关重要.
- 识别风险因素可以帮助制定有针对性的查策略.
研究的目的:
- 量化综合当前关于带插入 (VCI) 相关风险因素的证据.
- 通过了解与之相关的风险因素,加强对VCI的产前鉴定.
- 为查政策提供信息,特别是在没有普遍查绳索异常的环境中.
主要方法:
- 在MEDLINE,Cochrane图书馆和Scopus中进行了系统的文献搜索,截至2024年2月7日.
- 包括与VCI单独怀孕的观察性研究,与正常带插入的妊娠相比.
- 分析使用随机效应模型,报告风险比率 (RR) 和95%置信区间 (CI).
主要成果:
- 这项研究包括14项队列和4项病例控制研究,涵盖952,163例单独怀孕.
- 发现VCI的总体患病率为1.54%.
- 确定的重大风险因素包括辅助生殖技术 (RR, 2.32),无性伴侣 (RR, 1.21),吸烟 (RR, 1.14) 和胎盘前 (RR, 3.60).
结论:
- 辅助生殖技术,无胎儿,吸烟和胎盘前置已被证实是单独怀孕中VCI的重要危险因素.
- 这些发现支持针对风险人群进行VCI查的有针对性的方法.
- 结果可以指导开发更高效的查协议,以发现绳索插入异常.
相关概念视频
01:26Varicose Veins I: Introduction
2
Varicose veins, or varicosities, are abnormally dilated and twisted superficial veins caused by venous valve incompetence. This condition commonly affects the lower extremities, especially the saphenous veins, due to the higher pressure from prolonged standing and walking. However, varicosities can also occur in other areas, such as the esophagus, vulva, spermatic cords, and anorectal region.Etiology and typesPrimary varicose veins, often idiopathic, are more common in women due to inherent...
2
01:19Mitral Valve Prolapse III: Nursing Management
5
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
5
01:07Teratogenicity
2.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.4K
01:30Neurulation
41.7K
Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
41.7K
01:07Development of Blood Vessels
540
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
540