门静脉血栓在COVID-19:一个未被确诊的疾病?
Ismael El Hajra1, Elba Llop1,2,3, Santiago Blanco1
1Department of Gastroenterology and Hepatology, Hospital Universitario Puerta de Hierro Majadahonda, 28222 Madrid, Spain.
Journal of clinical medicine
|September 28, 2024
概括
COVID-19可能会增加门静脉血栓症 (PVT) 的风险,这是一个罕见的疾病. 早期诊断和抗凝治疗导致所有研究的PVT的COVID-19患者完全康复.
科学领域:
- 血管医学 血管医学
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
背景情况:
- COVID-19与血栓栓塞事件的增加有关.
- COVID-19与状静脉血栓症 (包括门静脉血栓症 (PVT)) 之间的联系需要进一步调查.
研究的目的:
- 确定COVID-19患者的门静脉血栓症 (PVT) 的患病率,患者特征,临床表现和结果.
主要方法:
- 对接受腹部对比度增强CT扫描的COVID-19阳性患者 (n=2987) 的回顾性观察性研究.
- 纳入标准:年龄大于18岁,CT在6个月内,RT-PCR后呈阳性,没有先前的脊柱静脉血栓形成.
- 总共有60名患者被选中进行分析.
主要成果:
- 在选定的COVID-19患者中,门静脉血栓塞 (PVT) 的患病率为5% (3/60).
- PVT患者的平均年龄为66.1岁,51.7%为男性. 两名患者没有可识别的PVT风险因素.
- 抗凝治疗导致100%的再通道化,在803天的随访期间没有观察到长期并发症.
结论:
- 门静脉血栓塞 (PVT) 是一种不常见的并发症,但其发生率可能在COVID-19患者中升高.
- 了解COVID-19中的PVT有助于早期诊断和管理.
- 及时抗凝药在COVID-19患者的PVT中是有效的.
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