阻塞性睡眠呼吸暂停对中风后并发症的影响:系统性审查和元分析
Nithin Kurra1, Nikhila Gandrakota2, Manju Ramakrishnan3
1Department of Neurology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Journal of clinical medicine
|September 28, 2024
概括
阻塞性睡眠呼吸暂停 (OSA) 没有显著增加整体中风后并发症. 然而,患有严重中风的OSA患者面临的并发症风险略高,需要进一步调查.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 心血管研究研究心血管研究
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 与中风的发展有关.
- 关于OSA对中风后并发症严重程度和发病率的影响的数据有限.
研究的目的:
- 系统地审查和分析OSA和中风后并发症之间的关系.
- 确定OSA是否影响各种中风后并发症的严重程度和发展.
主要方法:
- 从PubMed,Web of Science和Scopus. 来自2023年12月之前的研究的系统文献综述.
- 使用随机效应模型进行元分析与审查经理 5.4.1.1.
- 数据采用标准比率和95%置信区间进行聚合.
主要成果:
- 这项分析包括了9项研究.
- 与非OSA患者相比,OSA患者的中风后并发症 (认知障碍,痴呆,失眠,疲劳,抑郁,焦虑,复发性中风,死亡) 没有显著增加 (RR = 1.05,95% CI 0.97 至 1.13).
- 患有高中风严重程度和OSA患者的中风后并发症风险略高 (RR=1.06,95% CI 1.01至1.12).
结论:
- OSA可能会增加中风后并发症的风险,特别是在中风严重程度高的患者中.
- 需要进一步的研究才能充分了解OSA对中风后结果的影响.
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