结肠直肠癌和石暴露:一个女性健康的视角
Antonietta Porzio1,2, Alessandro Feola3, Cecilia Salzillo4
1Department of Mental and Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", Via Luciano Armanni 5, 80138 Naples, Italy.
Healthcare (Basel, Switzerland)
|September 28, 2024
概括
本次审查强调,接触石棉可能会增加女性的结直肠癌 (CRC) 风险,特别是那些在工业工作的人. 需要更多的研究来解决与石棉有关的CRC研究中的性别偏见.
科学领域:
- 职业健康 职业健康 职业健康
- 在瘤学瘤学.
- 环境流行病学环境流行病学
背景情况:
- 结肠直肠癌 (CRC) 通常被认为是一种
- 新出现的证据表明,女性可能面临某些CRC因子的更高风险.
- 暴露在石棉和女性CRC之间的联系是研究不足的.
研究的目的:
- 系统地审查有关女性中石棉相关的CRC发病率和死亡率的文献.
- 调查有关石棉和CRC现有研究中的潜在性别偏见.
主要方法:
- 系统的文献审查遵循PRISMA指南.
主要成果:
- 包括14项研究,其中涉及92例患有CRC的石棉暴露妇女.
- 受影响最多的女性是50岁以上,在钢铁和织等行业的职业接触.
- 在近一半的病例中,结肠是主要的瘤部位;三例还患有腹间皮质瘤.
结论:
- 在科学研究中,关于石棉和CRC的方法上存在性别偏见.
- 增加临床研究中的女性代表性对于理解石棉诱导的CRC至关重要.
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