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Updated: Jun 11, 2025

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
10:01

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Published on: November 28, 2017

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PRC1蛋白子复合体架构:专注于蛋白互动网络中不同PCGF子单元之间的相互作用

Nayla Munawar1, Kieran Wynne2,3, Giorgio Oliviero3

  • 1Department of Chemistry, College of Science, United Arab Emirates University, Al Ain 15551, United Arab Emirates.

International journal of molecular sciences
|September 28, 2024
PubMed
概括

这项研究研究了多聚抑制剂复合体1 (PRC1) 相互作用,揭示了不同的PCGF蛋白子单元如何影响细胞功能和染色质调节. 了解这些网络是表观遗传调节研究的关键.

关键词:
细胞NT2细胞NT2细胞这是PCGF的PCGF.在PRC1中,染色体调节 染色体调节表观遗传学是指表观遗传学.基质子的修改 基质子的修改免疫沉 免疫沉是一种质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量聚组组蛋白 (PcG) 是一种多组组蛋白.

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