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Updated: Jun 11, 2025

Production of Disulfide-stabilized Transmembrane Peptide Complexes for Structural Studies
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溶性ACE2的二硫化物键工程用于增强热稳定性

Yoon Soo Kim1, Myeongbin Kim1, Hye Min Park1

  • 1Department of Bioengineering, College of Engineering, Hanyang University, Seoul 04673, Republic of Korea.

International journal of molecular sciences
|September 28, 2024
PubMed
概括

研究人员设计了一种更稳定的可溶性ACE2 (sACE2) 蛋白质,以对抗SARS-CoV-2变种. 这种增强的SACE2-Fc保持了强大的结合亲和力,为未来的病毒威胁提供了广泛的治疗潜力.

关键词:
这就是SARS-CoV-2病毒.双硫化物键是一种二硫化物键.可溶性ACE2可以溶解.热稳定性增强 热稳定性增强不依赖变异的治疗方法.

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