PAK4NAMPT

Yiling Wang1, Audrey Minden1

  • 1Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

概括

包括KPT-9274在内的PAK4抑制剂不仅向PAK4,还向NAMPT,影响癌细胞生长. 这种双重抑制表明这些癌症治疗药物的复杂作用机制.

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