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Updated: Jun 11, 2025

Merging Absolute and Relative Quantitative PCR Data to Quantify STAT3 Splice Variant Transcripts
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Published on: October 9, 2016

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与自身免疫相关的SNP rs3024505 破坏B细胞中的STAT3结合,导致IL10失调

Aksinya N Uvarova1,2, Elina A Zheremyan1,2, Alina S Ustiugova2

  • 1Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.

International journal of molecular sciences
|September 28, 2024
PubMed
概括

一个接近IL10基因的遗传变异影响了免疫调节. 常见的变异增强了B细胞中互白素10 (IL10) 的产生,而风险的变异减少了它,可能会恶化炎症性疾病.

关键词:
B 细胞 B 细胞 B 细胞IL10 IL10 已经开始了在STAT3中,我们可以使用STAT3.自身免疫性疾病 自身免疫性疾病免疫调节 免疫调节监管SNP的SNP就是监管SNP.

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