药物过度使用头痛:管理的最新情况
Prut Koonalintip1,2,3, Katherine Phillips4, Benjamin R Wakerley2,3
1Division of Neurology, Department of Internal Medicine, Prince of Songkla University, Hatyai 90110, Songkhla, Thailand.
Life (Basel, Switzerland)
|September 28, 2024
概括
经常使用急性止痛药可以使头痛恶化,导致药物过量使用头痛 (MOH). 新的治疗方法为管理这种情况提供了希望,特别是在偏头痛患者中.
科学领域:
- 神经学 神经学
- 药理学 药理学是指药理学的学科.
背景情况:
- 长期使用急性疼痛药物治疗头痛可能会矛盾地增加头痛的频率.
- 药物过度使用头痛 (MOH) 是一个重大问题,特别是在使用和阿片类药物的偏头痛患者中.
研究的目的:
- 审查药物过量使用头痛 (MOH) 的负担,发展,病理生理学和治疗策略.
主要方法:
- 本综述审查了关于药物过度使用头痛的现有文献.
- 它综合了有关卫生部流行病学,机制和治疗方法的信息.
主要成果:
- 通过教育预防是关键,但已建立的MOH难以治疗.
- 停止急性药物治疗对大多数患者有好处,但很难实现.
- 无胺毒素A,CGRP向疗法,Gepants和Ditans在MOH和偏头痛管理方面表现有前途.
结论:
- 过度使用药物导致的头痛是一个复杂的临床挑战.
- 新型的预防和急性治疗,以及教育策略,对于改善MOH和偏头痛患者的治疗结果至关重要.
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