在六分钟步行测试中的表现不歧视在严重缺氧环境中的过度红细胞瘤患者
Rossela Alejandra Rojas-Chambilla1,2, Kely Melina Vilca-Coaquira1,2, Jeancarlo Tejada-Flores1,2
1Facultad de Medicina Humana, Universidad Nacional del Altiplano, Puno 21000, Peru.
International journal of environmental research and public health
|September 28, 2024
概括
过度的红细胞瘤 (EE) 并没有显著影响高海拔居民的六分钟步行测试 (6MWT) 的表现. 尽管血红素和血红素水平较高,但EE受试者与健康人相比,在5100米处保持了类似的运动能力和生命体征.
科学领域:
- 高海拔的生理学 高海拔的生理学
- 人类适应低氧的情况.
- 运动生理学 运动生理学
背景情况:
- 长期暴露于严重的缺氧 (例如,在高海拔地区) 会提高血红素 (Hct) 和血红蛋白度 ([Hb]).
- 这可能导致过度的红细胞症 (EE),这种疾病的特征是异常高的红细胞计数.
- EE可能会影响物理性能,特别是在苛刻的环境中.
研究的目的:
- 为了研究过度红细胞瘤 (EE) 和健康对照人群之间的六分钟行走测试 (6MWT) 性能差异.
- 评估EE对在极高海拔地区进行中度有氧运动时身体能力和生理反应的影响.
主要方法:
- 一项前性,横截面研究,涉及71名男性 (36名健康,25名EE),居住在秘鲁拉林科纳达的5100米处.
- 测量包括基底[Hb]和Hct水平,人体参数和6MWT性能 (距离,生命体征,呼吸障碍,使用博格尺度的疲劳).
主要成果:
- 与健康对照人群相比,EE受试者表现出明显更高的[Hb] (23.4 ± 1.6 g/dL与18.7 ± 1.2 g/dL相比) 和Hct (73.6 ± 5.9%与60.4 ± 7.1%) (p < 0.001).与健康对照人群相比,EE受试者表现出明显更高的[Hb] (23.4 ± 1.6 g/dL与18.7 ± 1.2 g/dL相比) 和Hct (73.6 ± 5.9%与60.4 ± 7.1%) (p < 0.001).
- 身体质量指数 (BMI) 或其他人体测量指标在两组之间没有发现显著差异.
- 6MWT距离和大多数生命体征都相似,但在测试期间,EE受试者的动脉氧和率始终较低.
结论:
- 在永久居住在高海拔地区的个体中,过度的红细胞瘤不会显著损害6MWT的性能.
- 在中度有氧运动期间,在生活在严重低氧环境中的EE受试者中保持了血液动力学控制.
- 高空适应可以减轻EE对运动能力的负面影响.
关键词:
安第斯山脉安第斯山脉的安第斯山脉拉林科纳达 (La Rinconada) 是一个城市.慢性山病是一种慢性山病.过度的红细胞化.血高位的血高位是什么血红蛋白 血红蛋白 是一个它们是高海拔地区的原住民.催眠症催眠症的催眠症是什么身体表现 身体表现 身体表现六分钟的行走测试更多相关视频
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