罗马尼亚患者对多发性骨髓瘤持续治疗的观点
Ruxandra Irimia1, Sorina Nicoleta Badelita2, Sinziana Barbu1,2
1Department of Hematology, "Carol Davila" University of Medicine and Pharmacy, 030167 Bucharest, Romania.
Journal of personalized medicine
|September 28, 2024
概括
持续的多发性骨髓瘤 (MM) 治疗改善了生存率,但影响了生活质量. 患者害怕停止治疗,因为担心复发,尽管经济和个人负担.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 患者报告的结果
背景情况:
- 持续治疗是多发性骨髓瘤 (MM) 的标准护理,改善了生存结果.
- 患者对持续的MM治疗对生活质量的影响的看法仍未得到充分研究.
研究的目的:
- 调查持续的MM治疗对患者报告的生活质量 (QoL) 的影响.
- 从患者的角度确定与长期MM治疗相关的具体挑战和好处.
主要方法:
- 这是一项基于问卷的研究,对155名接受持续治疗的MM患者进行了调查 (达拉图穆马布,蛋白酶抑制剂,免疫调节剂,双特异性抗体).
- 评估了治疗对个人和职业生活的定量和质量影响,并确定了影响QOL的关键副作用.
主要成果:
- 74.83%的患者报告了对生活质量的负面影响,并将财务负担和职业生活中断列为主要问题.
- 疲劳,失眠和骨疼痛是最具影响力的副作用;然而,由于害怕复发,患者在很大程度上避免停止治疗.
- 频繁的医院访问提供了心理安慰,超过70%的人表示害怕停止治疗.
结论:
- 持续的MM治疗,尽管它的负担,通常被患者接受,因为感知到的好处和恐惧复发.
- 医院监测提供了保证,患者重视频繁的临床接触所带来的心理舒适.
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