卵巢过度刺激综合征 (OHSS):叙述性审查和法律影响
Giuseppe Gullo1, Gaspare Cucinella1, Vukasin Stojanovic2
1Department of Obstetrics and Gynecology, Villa Sofia Cervello Hospital, IVF Unit, University of Palermo, 90146 Palermo, Italy.
Journal of personalized medicine
|September 28, 2024
概括
卵巢过度刺激综合征 (OHSS) 是辅助生殖技术 (ART) 中的一个严重风险. GnRH对抗剂协议显著降低了IVF期间严重的OHSS风险,但谨慎管理仍然至关重要.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 不孕症管理 不孕症管理
- 辅助生殖技术 (ART) 是一种辅助生殖技术.
背景情况:
- 全球不孕症发病率正在上升,需要像ART这样的先进治疗方法.
- 辅助生殖技术 (ART) 携带卵巢过度刺激综合征 (OHSS) 的风险,这可能是严重的并发症.
研究的目的:
- 审查卵巢过度刺激综合征 (OHSS) 的动态,管理和基于证据的指导方针.
- 在辅助生殖技术 (ART) 和体外受精 (IVF) 的背景下提供OHSS的全面概述.
主要方法:
- 从1990年到2024年,PubMed索引的文章进行了叙事审查.
- 搜索术语包括"OHSS"",卵巢过度刺激"",IVF"",GnRH"和"hCG",产生了111个相关来源.
主要成果:
- 造成OHSS的危险因素包括年轻,体重低以及多囊性卵巢综合征 (PCOS).
- 与 GnRH 激动剂长期协议相比,GnRH 抗剂协议大大降低了严重的OHSS 风险.
- 对于高风险患者,建议使用GnRH激动剂触发剂的结策略,尽管轻度/中度OHSS仍然可能发生.
结论:
- 早期诊断和管理OHSS,包括心理支持,至关重要.
- 坚持基于证据的指导方针和最佳实践对于临床护理和医疗法律保护至关重要.
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