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Updated: May 11, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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Published on: June 15, 2011

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全外体测序揭示了高风险神经母细胞瘤患者的新型候选驱动突变和潜在的可药性突变

Natakorn Nokchan1,2, Praewa Suthapot1,3,4, Pongsakorn Choochuen1,2

  • 1Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.

Journal of personalized medicine
|September 28, 2024
PubMed
概括

这项研究确定了神经母细胞瘤 (神经母细胞瘤) 中的新突变和可操作的标,神经母细胞瘤是一种常见的儿童癌症. 这些发现为分子驱动因素和高风险病例的潜在治疗策略提供了新的见解.

关键词:
癌症驱动基因是癌症的驱动基因.药物可用的突变.突变的签名突变的签名神经母细胞瘤的神经母细胞瘤身体变异的体质变异瘤突变负担的突变负担只有只有瘤.整体外因子测序的测序

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Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...