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Updated: Jun 11, 2025

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
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出生时的免疫生物标志物预测了大量出生队列中的下呼吸道感染风险

Ethan Mondell1, Gustavo Nino2,3, Xiumei Hong4

  • 1School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.

Pathogens (Basel, Switzerland)
|September 28, 2024
PubMed
概括

在带血液中的新生儿免疫因素,如干扰素 (IFNγ) 和瘤坏死因子-β (TNF-β),预测婴儿下呼吸道感染 (LRTI) 风险. 识别这些生物标志物可以帮助分层风险,并指导婴儿呼吸系统健康的治疗方法.

关键词:
出生的队列队列出生.这是带血,带血.细胞因子 细胞因子免疫生物标志物 免疫生物标志物这是下呼吸道感染.新生儿们的新生儿

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Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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