一个基于二酸的光传感器阵列,用于快速识别Lonicerae Japonicae Flos和Lonicerae Flos
Ying Bian1, Chenqing Xiang1, Yi Xu2
1School of Pharmacy, Hubei University of Science and Technology, Xianning 437100, China.
Molecules (Basel, Switzerland)
|September 28, 2024
概括
这项研究引入了一种新的光传感器阵列和机器学习,以准确区分Lonicerae japonicae flos (LJF) 和Lonicerae flos (LF). 这种方法可以确保正确识别这些传统的中国草药,防止药物替代.
科学领域:
- 分析化学 分析化学
- 生物化学 生物化学
- 药理学是指药理学,即药理学是指药理学.
背景情况:
- 龙 (Lonicerae japonicae flos,简称LJF) 和龙 (Lonicerae flos,简称LF) 是中国传统的草药,尽管外表相似,但具有独特的药用特性.
- 精确的区分至关重要,因为它们在临床应用中是不可互换的.
研究的目的:
- 开发一种快速准确的方法来区分LJF和LF.
- 为了利用先进的传感器技术和机器学习来进行草本认证.
主要方法:
- 设计了一个六通道光传感器阵列,使用基于库马林的指示器和二博酸火器.
- 用指标位移试验 (IDA) 来检测酸化合物.
- 优化了8个机器学习算法,其中线性差异分析 (LDA) 显示出最佳性能.
主要成果:
- 传感器阵列成功地根据不同的光回收模式区分了LJF和LF.
- 优化的机器学习模型在测试组中实现了100%的准确性,在交叉验证中达到98.21%的准确性.
- 该方法在区分两种草本物种方面表现出高效.
结论:
- 集成的光传感器阵列和机器学习方法为识别LJF和LF提供了强大的工具.
- 这项技术对含有多的食品和药品的分析和质量控制具有重大潜力.
- 确保准确识别传统中国草药,支持安全有效的药用.
关键词:
单鱼类 (Lonicerae) 的牙线有孤单的日语字母 (Lonicerae japonicae flos) 是一个日本字母.光传感器阵列是一组光传感器阵列.机器学习是机器学习.快速识别快速识别更多相关视频
09:45Locked Nucleic Acid Flow Cytometry-fluorescence in situ Hybridization LNA flow-FISH: a Method for Bacterial Small RNA Detection
Published on: January 10, 2012
25.3K
10:04Imaging Amyloid Tissues Stained with Luminescent Conjugated Oligothiophenes by Hyperspectral Confocal Microscopy and Fluorescence Lifetime Imaging
Published on: October 20, 2017
13.4K
相关概念视频
Labeling DNA Probes
8.1K
DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
8.1K
FISH - Fluorescent In-situ Hybridization
20.4K
Fluorescence in situ hybridization, or FISH, was developed in the early 1980s and has quickly become one of the most widely used techniques in cytogenetics. Labeled probes are used to bind complementary DNA or RNA sequences on a chromosome or in a region within a cell. Earlier, the probes could only be obtained by cloning or reverse transcription of a DNA template. Currently, the probe oligonucleotides can be synthesized synthetically. Additionally, with the advancement of optical techniques,...
20.4K
