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Updated: Jun 11, 2025

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在碳酸酶抑制剂的设计中享有特权的架构杂交

Daniela Secci1, Erica Sanna1, Simona Distinto1

  • 1Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, 09042 Cagliari, Italy.

Molecules (Basel, Switzerland)
|September 28, 2024
PubMed
概括

研究人员开发了新型的伊沙 thiazolidinone 杂交物,作为潜在的抗癌剂,向人类碳酸无水酶 (hCA) IX 和 XII. 这些化合物显示出有前途的纳米分子抑制活性,特定分子对这些与癌症相关的酶表现出高强度和选择性.

关键词:
硫胺基结合剂是基于硫胺的结合剂.碳酸无水酶抑制剂 碳酸无水酶抑制剂脚手架的混合化 架构的混合化

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