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Updated: Jun 11, 2025

Reverse Genetics Mediated Recovery of Infectious Murine Norovirus
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细胞N-Myristoyl转移酶是哺乳动物病毒繁殖所需的

Haydar Witwit1, Carlos Alberto Betancourt1, Beatrice Cubitt1

  • 1Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.

Viruses
|September 28, 2024
PubMed
概括

一种新的泛NMT抑制剂DDD85646通过破坏病毒聚集和进入,对危险的乳腺病毒如LCMV,JUNV和LASV表现出强大的抗病毒活性. 这表明N-myristoyltransferase抑制是一种有前途的广谱抗病毒策略.

关键词:
拉斯维亚拉斯维亚拉斯维亚 LASV在 LCMV 中,LCMV 是在N-myristoyl转移酶.这是一种抗病毒药物.乳腺病毒的病毒这就是Myristoylation.蛋白质酶体蛋白质组是什么

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