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Updated: Jun 11, 2025

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用HAM/TSP外体脉冲的树突细胞使CD4 T细胞敏感,以增强HTLV-1感染,诱导辅助T细胞极化,并降低细胞毒性T细胞反应

Julie Joseph1, Thomas A Premeaux2, Ritesh Tandon1

  • 1Department of Microbiology & Immunology, Drexel University College of Medicine, Philadelphia, PA 19129, USA.

Viruses
|September 28, 2024
PubMed
概括

来自HTLV-1感染细胞和HAM/TSP患者的外体细胞损害了免疫细胞的功能. 这些细胞外囊泡恶化了树突细胞和T细胞的反应,可能导致HTLV-1相关的骨髓病变/热带性帕拉帕雷斯进展.

关键词:
在HAM/TSPP上使用.在 HTLV-1 病毒中,在T细胞,T细胞.树突细胞是一种树突细胞.外基因组是外基因组的组成部分.

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