在受伤的老年人中输血:一个回顾性队列研究
Zhinan Liu1, Zaher Kmail2, Mairead Higgins3
1Department of Laboratory Medicine & Pathology, University of Washington School of Medicine, Seattle, Washington, USA.
Transfusion medicine (Oxford, England)
|September 28, 2024
概括
老年人 (≥55岁) 在受伤后更有可能接受输血. 然而,在治疗的前四小时内给予的血液制品数量取决于受伤严重程度,而不是年龄,在创伤复苏中显示年龄平等.
科学领域:
- 创伤护理和复苏治疗
- 老年急诊医学的紧急医疗.
- 血液产品输血协议 输血协议
背景情况:
- 老年人代表越来越多的创伤患者需要急性护理和输血.
- 越来越多的年龄和创伤中的血液产品利用之间的具体相互作用尚未得到充分理解.
- 了解这些动态对于优化对老化创伤人口的护理至关重要.
研究的目的:
- 调查年龄增长,输血产品和老年受伤成年人的死亡率之间的关系.
- 为了确定年龄是否影响急性创伤复苏的输血实践.
- 在创伤环境中评估不同年龄组的生存率和输血模式.
主要方法:
- 从一个大型区域创伤中心 (2011-2022) 追溯分析创伤数据.
- 数据包括患者人口统计,伤害严重程度,伤害机制和输血细节 (类型,时间,单位).
- 55岁及以上的患者按十年分层,并统计评估趋势 (p < 0.01).
主要成果:
- 在73,645名患者中,25,409名 (34.5%) 的年龄为55岁或以上.
- 与年轻患者相比,老年患者 (≥55) 输血 (24% vs 12.8%) 和死亡 (7.5% vs 2.9%) 的可能性是年轻患者的两倍,尽管受伤严重程度相似.
- 在前4小时内输血量取决于受伤严重程度,而不是年龄队列,直到94岁.
- 在最初的4小时内,所有年龄和输血强度的生存率超过50%.
结论:
- 55岁及以上的患者在创伤复苏中更频繁地接受输血.
- 在治疗的前4小时内服用的血液制品数量主要取决于受伤严重程度,而不是患者的年龄.
- 这项研究表明,在急性复苏实践中,血液产品的使用与年龄相匹配.
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