用较少的抗高血压药物进行最佳血压控制:主要在低风险高血压患者中实现
Zhanyang Zhou1, Huanhuan Miao1, Shijie Yang1
1Department of Cardiology, Heart Failure Center, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Journal of clinical hypertension (Greenwich, Conn.)
|September 28, 2024
概括
达到血压 (BP) 控制通常需要较少的药物对较低风险的患者. 强烈的高血压目标可以在最小的抗高血压药物负担下实现,这表明有利的风险概况.
科学领域:
- 心血管医学 心血管医学
- 高血压研究 高血压研究
- 公共卫生 公共卫生
背景情况:
- 高血压影响了54%的受试者.
- 有效的血压控制对心血管健康至关重要.
- 抗高血压药物负担与血压控制之间的关系需要进一步调查.
研究的目的:
- 评估血压控制与使用的抗高血压药物的数量之间的相关性.
- 在社区环境中确定影响高血压控制的因素.
- 评估血压控制状态和与心血管风险相关的药物负担.
主要方法:
- 对4991名来自马吉亚普社区的个人进行了横截面研究.
- 根据确定的门,将参与者分为受控和不受控制的BP组.
- 多变量逻辑回归分析,以确定与血压控制相关的因素.
主要成果:
- 在接受治疗的高血压患者中,55.7%的人实现了血压控制,其中23.15%的人达到最佳水平 (<130/80 mm Hg).
- 非控制组使用的抗高血压药物比控制组使用的抗高血压药物 (1.75) 多 (1.61).
- 与不良血压控制相关的因素包括年龄,男性性别,肥胖和前吸烟;使用降脂药物与更好的血压控制有关.
结论:
- 对于达到更严格的血压目标的患者,可能需要更少的抗高血压药物,这表明心血管风险概况较低.
- 一小部分接受治疗的患者是低风险个体,可以达到最佳的血压控制 (<130/80毫米升).
- 了解药物负担,血压控制和风险因素之间的相互作用对于个性化高血压管理至关重要.
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