一项基于人群的研究,研究甲状腺癌与慢性牙周炎的关联
Tzong-Hann Yang1,2,3,4,5, Yen-Fu Cheng3,5,6,7,8, Herng-Ching Lin9,10,11
1Department of Otorhinolaryngology, Taipei City Hospital, Taipei, Taiwan.
Journal of periodontology
|September 28, 2024
概括
慢性牙周炎与甲状腺癌的风险增加近两倍有关. 这项研究强调了口腔健康在癌症预防策略中的重要性,强调综合监测以获得更好的公共卫生结果.
科学领域:
- 流行病学 流行病学
- 在瘤学瘤学.
- 牙周病学 牙周病学
背景情况:
- 新出现的证据表明牙周炎与包括甲状腺癌在内的各种癌症之间存在联系.
- 对这种关联的研究还处于早期阶段,需要进一步的研究.
研究的目的:
- 为了研究慢性牙周炎和甲状腺癌之间的关联.
- 利用台湾长度健康保险数据库2010 (LHID2010) 进行基于人口的病例控制研究.
主要方法:
- 采用了病例控制研究设计,将2,775名甲状腺癌患者与8,325名对照进行匹配.
- 倾向性得分匹配考虑年龄,性别,收入,糖尿病,高血压,高脂血症,HPV感染和烟草使用障碍.
- 多变量逻辑回归模型评估了甲状腺癌和慢性牙周炎之间的关联.
主要成果:
- 在甲状腺癌患者 (38.5%) 与对照组 (24.1%) 相比,慢性牙周炎的患病率显著增加 (p < 0.001).
- 在甲状腺癌患者中,先前患有慢性牙周炎的几率比为1.991 (95% CI: 1.8162.184),表明几率几乎翻了一番.
- 这种关联在两性之间保持一致,男性的调整后的OR为1.991,女性为1.962.
结论:
- 慢性牙周炎被确定为甲状腺癌的潜在危险因素.
- 这些发现强调需要综合健康监测和包括口腔健康在内的预防策略.
- 提高公众对牙周炎相关的口腔健康风险的认识至关重要.
相关概念视频
01:23Chronic Pharyngitis
1.3K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
1.3K
01:15Teeth
343
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
343
01:19Psychoneuroimmunology: Diabetes and Cancer
25
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
25
01:21Tooth Anatomy
386
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
386
01:17Hormones and Bone Tissue
2.6K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.6K
00:59The Parathyroid Glands
1.9K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
1.9K