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相关概念视频

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

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Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
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Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

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Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
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Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Cardiomyopathy V: Interprofessional Care01:29

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Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
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Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

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Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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相关实验视频

Updated: Jun 11, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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新发病的左心室功能障碍在左子分支节奏之后.

Shunmuga Sundaram Ponnusamy1, Vithiya Ganesan2, Sudharshana Nagalingam3

  • 1Department of Cardiology, Velammal Medical College Hospital and Research Institute, Madurai, India.

JACC. Clinical electrophysiology
|September 28, 2024
PubMed
概括

新发病的左心室功能障碍 (NOLVD) 在左束枝节奏 (LBBP) 后发生在3.75%的患者中. 大多数病例是由于可逆原因造成的,例如传导系统捕获的损失,强调需要定期监测设备.

关键词:
在心房-心室延迟.左捆的分支节奏节奏,分支节奏.输电系统捕获输电损失的情况.新发病的左心室功能障碍

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科学领域:

  • 心脏病学 心脏病学
  • 电子生理学 电子生理学
  • 这是心脏衰竭.

背景情况:

  • 左捆枝节奏 (LBBP) 是一种提供稳定的参数的节奏技术,被认为是传统右心室节奏的替代品.
  • 此外,LBBP还被探索为心力衰竭患者的心脏再同步治疗的方法.

研究的目的:

  • 为了确定LBBP后新出现的左心室功能障碍 (NOLVD) 的发生率和原因.
  • 在最初正常的左心室 (LV) 功能和以前受损但正常化的LV功能患者中调查NOLVD.

主要方法:

  • 分析了426名患者的队列,这些患者接受了成功的LBBP治疗,以诊断症状性胸腺节律不良或CRT.
  • 患者被分为基线正常的LV功能和LBBP后正常化的LV功能.
  • 传导系统捕获的损失 (LOCSC) 被定义为在值测试期间失去右束分支块模式和捕获过渡.

主要成果:

  • 新发病的左心室功能障碍 (NOLVD) 在3.75%的患者 (426例中16例) 中观察到.
  • 在62.5%的病例中,NOLVD的主要原因是传导系统捕获损失 (LOCSC).
  • 重新干预,包括重定位和AV延迟优化,在所有受影响的患者中成功恢复了LV功能.

结论:

  • 新发病的左心室功能障碍 (NOLVD) 可以发生在左束枝节奏 (LBBP) 后,即使在以前正常或恢复的LV功能的患者中.
  • 可逆原因,特别是传导系统捕获损失 (LOCSC),是NOLVD的重要贡献者.
  • 在设备诊所进行定期的后续评估对于在LBBP后早期发现和管理NOLVD至关重要.