卵巢储备不会影响自然受孕:不孕妇女的见解
Giulia Galati1, Marco Reschini2, Alessandra Chine'3
1Department of Maternal and Child Health and Urology, Sapienza University, Viale Regina Elena, 324, 00161, Rome, Italy. giulia.galati@uniroma1.it.
Archives of gynecology and obstetrics
|September 28, 2024
概括
卵巢储备不会影响自然受孕的机会. 这项研究发现,有原因不明的不孕症和有男性不孕症的女性之间的卵巢储备标记没有显著差异,这表明.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 人类生育能力研究 研究人类生育能力
背景情况:
- 关于卵巢储备与自然怀孕的关系的现有证据是不确定的,一些研究表明,如果月经周期规律,就没有联系.
- 以前的研究存在方法上的局限性,需要对卵巢储备和自然受孕进行进一步的研究.
研究的目的:
- 调查卵巢储备和不孕妇女自然受孕的可能性之间的关系.
- 为了比较卵巢储备生物标志物之间的妇女,不明原因的不孕不育和那些严重的男性不孕不育.
主要方法:
- 这是一项回顾性研究,将252名患有不明原因不孕症的女性与252名患有严重男性不孕症的年龄和时间匹配的女性进行了比较.
- 卵巢储备的评估是使用抗穆勒尔激素 (AMH),二毛囊数 (AFC) 和2-3日血清毛囊刺激激素 (FSH).
- 主要结局:女性血清AMH<0.7 ng/mL的发生频率.
主要成果:
- 在不明原因不孕症和男性不孕症组之间,没有发现AMH,AFC或FSH水平的显著差异.
- 在不明原因的不孕症中,AMH<0.7 ng/mL的频率为10%,在男性不孕症中为14% (p=0.28).
- 在未解释不育症中,低AMH的调整几率比为0.76 (95%CI:0.44-1.33).
结论:
- 卵巢储备不是影响自然受孕概率的重要因素.
- 研究结果表明,医生和患者应该重新考虑卵巢储备在自然生育辅导中的作用.
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