周围神经刺激用于神经病痛管理:叙述性综述
Zhangyan Mao1,2,3,4, Jing Lv2,3,4, Yan Sun1,2,3,4
1Department of Pain, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277, Jiefang Avenue, Wuhan, 430022, China.
Pain and therapy
|September 28, 2024
概括
周围神经刺激 (PNS) 为控制神经病痛 (NP) 提供了一个有前途的替代方案,显示出显著的疗效,副作用很少. 需要进一步进行高质量的试验,以优化这种创新的疼痛管理方法.
科学领域:
- 神经学 神经学
- 疼痛管理 疼痛管理
- 生物医学工程 生物医学工程
背景情况:
- 神经病痛 (NP) 影响全球6.90%10.00%,通常由传统药理学管理不充分.
- 周围神经刺激 (PNS) 成为NP的可行的替代治疗方法.
- 由于目前的药理干预措施的局限性,对有效的NP治疗存在重大需求.
研究的目的:
- 审查外围神经刺激 (PNS) 治疗神经病痛 (NP) 的治疗疗效.
- 探索缓解疼痛的PNS背后的机制.
- 确定NP管理中PNS的挑战和未来研究方向.
主要方法:
- 关于神经病痛PNS现有文献的叙述性综述.
- 临床证据总结PNS在诸如三角神经疼痛和后神经疼痛等疾病中的疗效.
- 讨论PNS机制,包括Aβ纤维激活和神经递质调制.
主要成果:
- PNS在治疗各种神经病痛疾病方面表现出显著的治疗效果.
- 通过外围和中央通道提供疼痛缓解,并报告了最小的副作用.
- 证据支持PNS作为一个有前途的模式,尽管进一步的研究是指定的.
结论:
- 周围神经刺激 (PNS) 是对神经病痛 (NP) 的一个非常有前途的治疗方法.
- 优化刺激参数和进一步的随机对照试验至关重要.
- PNS需要继续调查,以确定其在NP临床实践中的最终作用.
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