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杜申肌肉发育不良症的学龄前男孩的细度和粗度运动技能是如何发展的?

Jasmine Hoskens¹, Ines Vandekerckhove², Liesbeth De Waele³

¹KU Leuven, Department of Rehabilitation Sciences, Research Group for Neurorehabilitation (eNRGy), Herestraat 49, Leuven 3000, Belgium; UHasselt, Faculty of Rehabilitation Sciences, Rehabilitation Research Centre (REVAL), Campus Diepenbeek, Agoralaan, Diepenbeek, Hasselt 3590, Belgium.

Research in developmental disabilities

|September 28, 2024

概括

与同龄人相比,患有杜恩肌肉发育不良 (DMD) 的男孩在细致和粗运动技能方面表现出缺陷. 认知显著影响运动技能的发展,这表明早期干预需要更广泛的精神运动方法.

科学领域:

儿科神经学儿科神经学
发育儿科发育儿科
康复医学康复医学康复医学

背景情况:

患有杜氏肌肉发育不良 (DMD) 的男孩表现出显著的细致和粗运动障碍.
目前对DMD的早期干预主要集中在粗运动技能上,可能会忽视细运动发展.

研究的目的:

为了研究诊断为DMD的学龄前男孩的早期运动发育.
检查认知功能对DMD年轻男孩运动技能的进展的影响.

主要方法:

一组17名患有DMD的男孩 (11个月至6岁) 使用贝利婴儿和幼儿发展量表 (Bayley-III),皮博迪发育运动量表 (PDMS-II) 和运动功能量表 (MFM-20) 进行了评估.
用线性混合效应模型 (LMM) 分析了细度和粗度运动技能的纵向变化,并将认知功能作为共同变量纳入其中.

主要成果:

与典型发育的同龄人相比,患有DMD的男孩在精细运动和粗运动技能方面得分明显较低 (p<0.001).
运动发育的轨迹在不同的子尺度上有所不同.
发现认知能力对各种运动子表现有显著影响 (p=0.002-0.04).

结论:

患有DMD的学龄前男孩不能达到他们通常发育的同行的功能水平.
认知在DMD中运动技能的发展轨迹中起着关键作用.
对于早期干预和未来的临床试验设计,建议采用综合性精神运动方法,整合细致和粗运动技能,并考虑认知影响.

关键词:

认知认知是一种认知.杜恩肌肉发育不良 (DMD)早期发展早期发展婴儿婴儿婴儿运动技巧运动技巧幼儿园儿童学龄前儿童幼儿幼儿的孩子幼儿的孩子

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