三甲基胺N-氧化物促进PERK介导的内皮细胞-介质细胞过渡和亡,从而加剧动脉样硬化

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Updated: May 2, 2026

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
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Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling

Published on: August 3, 2018

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Wang Bingyu1, Qiu Jun1, Liu Bingyang1

  • 1Department of Cardiovascular, Ningbo Medical Center Lihuili Hospital, Ningbo University, Ningbo, China.

International immunopharmacology
|September 28, 2024
PubMed
概括

三甲基胺N-氧化物 (TMAO) 通过促进内皮-介质酶过渡 (EndMT) 来恶化动脉样硬化. 准PERK通路可能提供针对TMAO诱导的心血管损伤的治疗策略.

关键词:
激活的转录因子-3动脉样硬化是一种动脉样硬化.细胞内皮 - 介质细胞过渡佩克 (Perk) 是一个名为"Perk"的东西.有反应性氧物种的反应性氧物种.三甲基胺N-氧化物

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