在临床时间内生物识别参数的行为
M Atar-Vardi1, B Dubinsky-Pertzov1, A Shemer1
1Department of Ophthalmology, Shamir Medical Center, Zerifin, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Journal francais d'ophtalmologie
|September 28, 2024
概括
像轴长度 (AL) 和前腔深度 (ACD) 这样的生物识别测量在一天中波动. 眼睛生物学的这种日间变化可能会影响白内障手术的眼内透镜计算.
科学领域:
- 眼科医生 眼科 眼科
- 生物医学工程 生物医学工程
- 视光学测量 视光学测量 视光学测量
背景情况:
- 准确的生物识别测量对于成功计算白内障手术中的眼内透镜 (IOL) 功率至关重要.
- 以前的研究还没有完全量化关键眼部生物识别参数的日间变化.
研究的目的:
- 为了评估和量化轴长度 (AL),前腔深度 (ACD),中角膜厚度 (CCT) 和白至白 (WTW) 距离的日间变化.
- 评估这些日间变化对白内障手术后折射结果的潜在影响.
主要方法:
- 一项回顾性队列研究分析了21,975个生物识别检查,来自8611名接受白内障手术前测量的患者,使用IOL Master 700.
- 眼睛的参数 (AL,ACD,CCT,WTW) 被每小时评估,并分为早上 (7-9 AM) 和下午 (12-3 PM) 的时间段.
- 统计分析,包括一个通用的线性混合模型,用于确定日间变化的意义.
主要成果:
- 所有测量的生物识别参数 (AL,ACD,CCT,WTW) 都显示了统计学上显著的白天增加 (P<0.001).
- 轴长 (AL) 呈现出最显著的日间变化,从23.64±1.5毫米增加到24.01±1.76毫米.
- 即使在混合效应模型中对潜在混因素进行调整后,观察到的日间变化仍然很大.
结论:
- 在标准办公时间内测量的关键眼部生物识别参数中存在显著的日间波动.
- 生物识别测量的时间可能会影响折射可预测性和有效透镜位置 (ELP) 计算.
- 需要进一步调查,以确定生物识别的最佳时间,以提高白内障手术中的折射精度.
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