冬天出生:在瑞士早期精神病队列中,功能表现不佳的因素
Romeo Restellini1, Philippe Golay2, Raoul Jenni3
1Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; Service of Emergency Medicine, Department of Acute Medicine, Geneva University Hospitals, Geneva, Switzerland.
Schizophrenia research
|September 28, 2024
概括
冬天出生的人患早期精神病的风险更高,功能表现更差. 这种季节性出生效应与明显的临床症状有关,影响长期康复.
科学领域:
- 精神病学是一个精神病学.
- 流行病学 流行病学
- 神经科学是一个神经科学.
背景情况:
- 冬天出生是精神分裂症的已知危险因素.
- 冬天出生和早期精神病之间的联系需要进一步调查.
研究的目的:
- 确定冬季分娩是否会增加早期精神病的风险.
- 根据出生季节,检查早期精神病患者的功能和临床结果.
主要方法:
- 在瑞士对222名早期精神病患者进行前性研究.
- 与一般人口的出生季度的比较.
- 全球功能评估 (GAF) 和积极和消极综合征量表 (PANSS) 评价在三年内得分.
主要成果:
- 较高比例的早期精神病患者出生在冬季.
- 冬天出生的患者在6个月,24个月和36个月时显示GAF得分明显较低.
- 冬天出生的患者表现出较少的阳性症状 (PANSS阳性子级).
结论:
- 冬季分娩与早期精神病的功能性结果较差有关.
- 在精神病中,明显的症状可能与冬季分娩有关.
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