Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Intralumenal Vesicles and Multivesicular Bodies01:38

Intralumenal Vesicles and Multivesicular Bodies

3.4K
Intraluminal vesicles (ILVs) are small vesicles 50-80 nm in diameter formed during the maturation of early endosomes. A specialized endosome containing numerous ILVs is called a multivesicular body (MVB). ILVs contain internalized molecules such as antigens, nucleic acids, proteins, and metabolites. Some of these molecules are released from the MVBs inside exosomes and are transported to other cells. Other MVBs contain molecules that are retained in the ILVs and are later degraded within the...
3.4K
Overview of Exosomes01:36

Overview of Exosomes

2.7K
Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...
2.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Genome-wide identification of the PIF gene family in broomcorn millet (Panicum miliaceum) highlights PmPIF5 as a candidate regulator of photoperiod responses.

BMC plant biology·2026
Same author

Comprehensive analysis of the sucrose nonfermenting 1-related protein kinase 2 gene family in broomcorn millet (Panicum miliaceum L.) under abiotic stress conditions.

BMC genomics·2025
Same author

ACY1 Downregulation Enhances the Radiosensitivity of Cetuximab-Resistant Colorectal Cancer by Inactivating the Wnt/β-Catenin Signaling Pathway.

Cancers·2022
Same author

Autoantibody panel on small extracellular vesicles for the early detection of lung cancer.

Clinical immunology (Orlando, Fla.)·2022
Same author

Impaired Self-Referential Cognitive Processing in Bipolar Disorder: A Functional Connectivity Analysis.

Frontiers in aging neuroscience·2022
Same author

Serum macrophage inhibitory cytokine-1 serves as a novel diagnostic biomarker of early-stage colorectal cancer.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals·2021

相关实验视频

Updated: Jun 11, 2025

Setting a Successful Sorting for Extracellular Vesicle Isolation
08:37

Setting a Successful Sorting for Extracellular Vesicle Isolation

Published on: October 11, 2024

949

细胞外囊泡自身抗体 细胞外囊泡自身抗体

Yan Hua1, Panpan Jiang2, Chunyang Dai1

  • 1Department of Laboratory Medicine, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230031, China; Department of Laboratory Medicine, Anhui Provincial Cancer Hospital, Hefei, Anhui, 230031, China; Core Unit of National Clinical Research Center for Laboratory Medicine of China, Hefei, Anhui, 230001, China.

Journal of autoimmunity
|September 28, 2024
PubMed
概括

携带自我抗原的细胞外囊 (EV) 与自身抗体形成免疫复合体,称为EV自身抗体. 这些复合体与自身免疫性疾病和癌症有关,提供潜在的诊断标记.

关键词:
抗原是一种抗原.自动抗体是一种自身抗体.自身免疫性疾病是一种自身免疫性疾病.癌症 癌症 癌症 癌症细胞外囊泡中的细胞外囊泡.

更多相关视频

Flow Cytometric Analysis of Extracellular Vesicles from Cell-conditioned Media
08:32

Flow Cytometric Analysis of Extracellular Vesicles from Cell-conditioned Media

Published on: February 12, 2019

13.7K
Rapid Fluorescence-based Characterization of Single Extracellular Vesicles in Human Blood with Nanoparticle-tracking Analysis
09:16

Rapid Fluorescence-based Characterization of Single Extracellular Vesicles in Human Blood with Nanoparticle-tracking Analysis

Published on: January 7, 2019

9.8K

相关实验视频

Last Updated: Jun 11, 2025

Setting a Successful Sorting for Extracellular Vesicle Isolation
08:37

Setting a Successful Sorting for Extracellular Vesicle Isolation

Published on: October 11, 2024

949
Flow Cytometric Analysis of Extracellular Vesicles from Cell-conditioned Media
08:32

Flow Cytometric Analysis of Extracellular Vesicles from Cell-conditioned Media

Published on: February 12, 2019

13.7K
Rapid Fluorescence-based Characterization of Single Extracellular Vesicles in Human Blood with Nanoparticle-tracking Analysis
09:16

Rapid Fluorescence-based Characterization of Single Extracellular Vesicles in Human Blood with Nanoparticle-tracking Analysis

Published on: January 7, 2019

9.8K

科学领域:

  • 免疫学 免疫学 免疫学
  • 细胞生物学 细胞生物学
  • 在瘤学瘤学.

背景情况:

  • 自身抗体是B细胞对自身抗原产生的蛋白质.
  • 细胞外囊泡 (EVs) 由细胞释放出来,在体液中发现.
  • EVs可以呈现自我抗原,影响自身抗体的产生和免疫复合体的形成.

研究的目的:

  • 审查关于EVs,自身抗体和EV抗原的当前知识.
  • 要突出EV自身抗体的形成和功能.
  • 讨论它们在自身免疫性疾病和癌症中的作用.

主要方法:

  • 对EV和自身抗体现有研究的文献综述.
  • 综合有关EV自身抗体形成和功能的信息.
  • 对疾病病原和诊断中的潜在作用的分析.

主要成果:

  • 装有自我抗原的EV可以与自身抗体 (EV自身抗体) 形成功能性免疫复合体.
  • EV自身抗体参与了自身免疫性疾病和癌症的发病过程.
  • 这些复合体代表了潜在的非侵入性生物标志物,用于疾病诊断和预后.

结论:

  • 在疾病发展中,EV自身抗体具有重要作用.
  • EV自身抗体显示出作为诊断和预后生物标志物的前景.
  • 需要进一步的研究来阐明它们的分子特征和疾病贡献.