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神经纤维光链作为突尼斯多发性硬化症患者的诊断和预测生物标志物

Saloua Mrabet1, Ikram Sghaier2, Amira Souissi1

  • 1Neurology Department, LR18SP03, Razi University Hospital, 1 rue des orangers, Manouba, Tunis 2010, Tunisia; Faculty of Medicine of Tunis, University of Tunis El Manar, 15, Rue Djebel Lakhdhar, La Rabta, Tunis 1007, Tunisia; Clinical Investigation Center (CIC) "Neurosciences and Mental Health", Razi University Hospital, 1 rue des orangers, Manouba, Tunis 2010, Tunisia.

Multiple sclerosis and related disorders
|September 28, 2024
PubMed
概括

脑脊液和血清中神经纤维光链 (NfL) 水平是评估多发性硬化症 (MS) 活动和预测突尼斯患者疾病进展的宝贵生物标志物.

关键词:
生物标志物生物标志物障碍障碍是指残疾人的情况.多发性硬化症是多发性硬化症.神经纤维纤维是一种神经纤维.突尼斯人就是突尼斯人.

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The intermediate filaments are an essential component of the cytoskeleton. Presently six types of intermediate filament have been identified. Type I and II are acidic and basic keratin proteins. Type III is of mesodermal origin and comprises four proteins: vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Vimentin is commonly found in mesenchymal cells, desmin in muscle cells, GFAP in astrocytes, while peripherin is found in peripheral nervous system neurons (PNS). Type...