短期暴露于PM2.5成分,极端温度事件和中风死亡率
Boning Deng1, Lifeng Zhu1, Yuanyuan Zhang2
1Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Public Health, Wuhan University of Science and Technology, Wuhan 430065, China.
The Science of the total environment
|September 28, 2024
概括
细颗粒物 (PM2.5) 污染和极端温度事件 (ETE) 增加中风死亡. 热浪与PM2.5成分相结合显示出协同效应,显著增加中风死亡风险.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 毒理学 毒理学 毒理学
背景情况:
- 细颗粒物 (PM2.5) 和极端温度事件 (ETE) 是重要的环境健康风险.
- 虽然PM2.5质量与中风死亡率有关,但其成分的影响和与ETE的相互作用在全球范围内仍未得到充分研究.
研究的目的:
- 调查短期暴露于PM2.5成分和中风死亡率之间的关联.
- 检查PM2.5成分和ETE对中国东部中风死亡率的独立和相互作用影响.
主要方法:
- 使用了时间分层的病例交叉设计,其中有320372例中风死亡 (2016-2019).
- 每天评估的PM2.5成分 (BC,OM,NH4+,SO42-,NO3-) 和12个ETE (热浪,寒流).
- 采用了条件后勤回归,并使用REOI,AP和SI指标评估了交互效应.
主要成果:
- PM2.5成分,特别是酸盐 (NO3-),与中风死亡率的增加有显著的关联.
- 热浪和寒冷都增加了中风死亡风险,而热浪显示出更高的风险增加.
- 在热浪和PM2.5成分 (特别是无机气溶) 之间观察到协同效应,显著增加中风死亡风险.
结论:
- 短期暴露于PM2.5成分和ETE独立地提高中风死亡率.
- 热浪与PM2.5成分相互作用,增加中风死亡的风险.
相关概念视频
Decreased Body Temperature
602
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
602
Homeostatic Imbalances in Body Temperature
111
Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
111
Factors Affecting Body Temperature
3.9K
As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may include:
Factors may include:
3.9K
Increased Body Temperature
645
A body temperature above 38°C (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
645
Biological Effects of Radiation
15.3K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
15.3K
Psychoneuroimmunology: Cardiovascular Disease
26
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
26


