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Updated: Jun 11, 2025

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氨酸/奇托桑微囊被空心CuS纳米颗粒封闭,用于NIR/pH双响应药物释放

Wenhui Chen1, Jiayao Wang1, Chiyin Zhang1

  • 1School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, China; Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.

International journal of biological macromolecules
|September 28, 2024
PubMed
概括

研究人员开发了使用 Hyaluronic 酸和 Chitosan 进行药物输送的双响应微囊. 这些对pH/NIR反应的载体显示出高药载荷和可用于潜在组合治疗的受控释放.

关键词:
基托桑是一种酸盐.空洞的CuS纳米粒子是什么?氨酸是什么? 氨酸是什么?一层一层的层次.在 NIR/pH 响应能力上.

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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