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Updated: Jun 13, 2025

High-throughput Identification of Gene Regulatory Sequences Using Next-generation Sequencing of Circular Chromosome Conformation Capture 4C-seq
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人类基因组中富含G4形成的重复与强大的协调良好的转录和减少癌症转录组变异有关

Ruth B De-Paula1, Albino Bacolla2, Aleem Syed2

  • 1Graduate School of Biomedical Sciences, Baylor College of Medicine, Houston, Texas, USA; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

The Journal of biological chemistry
|September 28, 2024
PubMed
概括

基因起始点附近的G-四重复 (G4) DNA结构与人类更高,更稳定的RNA表达有关. 这种人类基因组特征可以解释基因表达差异和减少癌症变异.

关键词:
在G-quadruplex中使用.生物信息学是一种生物信息学.癌症 癌症 癌症 癌症 癌症表观遗传学是指表观遗传学.基因表达的基因表达方式遗传性疾病是一种遗传性疾病.非B型DNA的DNA是非B型DNA的

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