同时的周围假肢关节感染和传染性内心炎:患病率,危险因素和临床表现
Michael E Held1, Jeffery B Stambough1, Zachary A McConnell1
1Department of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas; Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
The Journal of arthroplasty
|September 28, 2024
概括
同时的周围假肢关节感染 (PJI) 和传染性内心炎 (IE) 是罕见但严重的,导致更长的住院和更高的死亡率. 对于PJI患者来说,迅速的IE工作非常重要.
科学领域:
- 传染性疾病 传染性疾病
- 整形外科手术 整形外科手术
- 心脏病学 心脏病学
背景情况:
- 血源性细菌传播理论上可以导致并发性感染,如传染性内心炎 (IE) 和周围假肢关节感染 (PJI).
- 关于PJI和IE同时发生的文献很少.
- 这项研究调查了PJI和IE患者的患病率,并发症和临床表现.
研究的目的:
- 为了确定并发PJI和IE的流行率.
- 分析与同时PJI和IE相关的并发症.
- 描述PJI和IE患者的临床表现和结果.
主要方法:
- 在2015年7月至2020年12月期间,追溯识别了655名PJI患者.
- 分类为两组:具有 IE 的 PJI (PJI + IE) 和没有 IE 的 PJI (PJI).
- 对临床结果,并发症和遵守修改后的杜克标准的分析.
主要成果:
- 9名患者 (1.4%) 被诊断为PJI + IE.
- PJI + IE 组表现出显著更高的C-反应蛋白水平,Elixhauser并发病率得分,住院时间和出院后2年死亡率.
- 在PJI + IE组中观察到伴随性疾病的频率增加,包括贫血,凝血病,复杂糖尿病,电解质障碍,神经疾病,,功能衰竭和膜疾病.
结论:
- 同时的PJI和IE虽然很少见,但代表了与增加的发病率和死亡率相关的严重疾病.
- 这些发现强调了在患有PJI的患者中考虑和调查IE的重要性.
- 修改后的杜克标准对于在PJI的背景下诊断IE是有效的.
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