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Updated: Jun 11, 2025

Isolation of CD4+ T-cells and Analysis of Circulating T-follicular Helper cTfh Cell Subsets from Peripheral Blood Using 6-color Flow Cytometry
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探索慢性淋巴细胞白血病中T毛囊辅助细胞水平的预后价值

Rui Zhang1, Sha Guo1, Jianhua Qu2

  • 1Hematology Center, The First Affiliated Hospital of Xinjiang Medical University, No. 137 Liyushan South Road, Urumqi, 830054, Xinjiang, China.

Scientific reports
|September 28, 2024
PubMed
概括

毛囊T辅助细胞 (Tfh) 影响慢性淋巴细胞白血病 (CLL) 的进展. 较高的Tfh细胞水平与CLL患者的更好的预后相关,识别了关键的预后标志物.

关键词:
慢性淋巴细胞白血病 慢性淋巴细胞白血病预后基因是指预后基因的基因.在 Tfhfh Tfh时间到第一次治疗.

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T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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