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Updated: Jun 11, 2025

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
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向CircAURKA通过增强CTNNB1蛋白降解来预防结直肠癌的进展

Zhenqiang Sun1,2, Pengyuan Dang3,4, Yaxin Guo5

  • 1Department of Colorectal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. fccsunzq@zzu.edu.cn.

Oncogene
|September 28, 2024
PubMed
概括

像cirCAURKA这样的循环RNA (circRNAs) 通过稳定CTNNB1蛋白来驱动结直肠癌 (CRC) 的进展,促进瘤生长和转移. 这一发现为CRC治疗提供了新的点.

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