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Updated: Jun 11, 2025

Genome Engineering of Primary Human B Cells Using CRISPR/Cas9
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优化为B细胞成熟的单击基因组编辑将其特异性重定向到瘤抗原

Natsuko Ueda1, Marine Cahen1,2, Jenny Leonard1

  • 1INSERM U 1236, University of Rennes 1, Etablissement Français du Sang, 35000, Rennes, France.

Scientific reports
|September 28, 2024
PubMed
概括

研究人员开发了一种新的单链免疫球蛋白 (Ig) 磁带,用于为癌症免疫疗法设计B细胞. 这种方法有效地重新连接B细胞受体 (BCRs) 和分泌Ig,用于向瘤治疗.

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