在美国成年人中,氧化平衡得分和女性喘之间的相关性
Xiao Qi1, Tianlei Zhou2, Jianlei Tang3
1Rehabilitation Department, WuJin Hospital Affiliated with Jiangsu University, WuJin Clinical College of Xuzhou Medical University, Changzhou, 213017, Jiangsu, P.R. China.
Scientific reports
|September 28, 2024
概括
较高的氧化平衡得分 (OBS) 与美国成年女性喘风险降低有关. 这表明OBS可能是预防喘发展的保护因素,特别是在前吸烟者中.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 喘是一个重要的公共卫生问题,特别是在女性中.
- 氧化应激对喘病原有作用.
- 氧化平衡与喘风险之间的关联需要进一步研究.
研究的目的:
- 调查氧化平衡得分 (OBS) 与美国成年女性喘发病率之间的关系.
- 为了确定OBS是否作为预防喘发展的保护因素.
主要方法:
- 采用2001-2018年国家健康和营养检查调查 (NHANES) 数据进行的横截面研究.
- 分析包括17,582名女性参与者,其中2,795人被诊断患有喘.
- 采用了多重物流回归,受限立方线和子组分析.
主要成果:
- 在OBS和女性喘发病率 (OR=0.99) 之间观察到负相关性.
- 与最低四分位数 (Q2:0.88,Q3:0.84,Q4:0.82) 相比,OBS较高的四分位数显示喘的几率显著降低.
- 显示了OBS和喘之间的线性关系;在前吸烟者中发现了保护作用.
结论:
- 氧化平衡得分升高与美国成年女性喘发病率较低有关.
- OBS可能是喘发展的保护因素.
- 研究结果表明,控制氧化平衡具有潜在的益处,对戒烟在预防喘方面有着具体的意义.
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