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Updated: Jun 11, 2025

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环胺以依赖结合位置的方式调节光滑受体活性

Kihong Kim1, Prateek D Bansal1, Diwakar Shukla2,3,4,5,6

  • 1Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.

Communications biology
|September 28, 2024
PubMed
概括

环胺作为CRD的SMO激动剂和TMD的对抗剂. 分子模拟揭示了对特定SMO域的环胺结合如何调节刺信号传递和胆固醇运输.

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