从奶酪乳清中发酵乙醇的工艺扩展模拟和技术经济评估
Mattia Colacicco1, Claudia De Micco1, Stefano Macrelli2,3
1Department of Bioscience, Biotechnology and Environment, University of Bari Aldo Moro, Via Edoardo Orabona, 4, 70125, Bari, Italy.
Biotechnology for biofuels and bioproducts
|September 28, 2024
概括
这项研究模拟了乳酪乳糖处理以生产乙醇的方法,发现乳酪乳糖的门费显著降低了乙醇成本. 实施这一过程作为现有设施的插件,可以进一步优化乙醇生产的经济性.
科学领域:
- 生物技术和生物工程 生物技术和生物工程
- 环境科学与工程环境科学与工程
- 化学工程是化学工程的重要组成部分.
背景情况:
- 欧盟奶酪乳糖产量在2022年超过5500万,造成富含乳糖的废水问题.
- 通过膜过和其组成部分作为发酵原料进行的奶酪乳清处理.
- 开发了一个模拟模型,用于工业规模的设施在意大利加工539m3/day的奶酪乳糖.
研究的目的:
- 模拟和评估一个工业规模的奶酪乳糖价值化过程的技术经济可行性.
- 评估不同奶酪乳糖采购模式 (门费与原材料成本) 对乙醇生产经济的影响.
- 为了确定从乳糖中产生乙醇的最佳发酵条件.
主要方法:
- 开发了一种模拟模型,将实验数据整合到使用Kluyveromyces marxianus的乙醇发酵中.
- 模拟奶酪乳清通过膜过进行蛋白质和乳糖回收的预处理.
- 包括下游无水乙醇生产,无氧消化和热电联合发电.
- 对经济参数进行了技术经济评估和敏感性分析,包括奶酪乳糖门费.
主要成果:
- 膜过回收了56%的乳清蛋白缩物和缩乳糖.
- 模拟了基于乳糖 (YE/L),生物质产量和最终乳糖度的乙醇产量的三个场景.
- 最佳情景 (YE/L = 0.45 g/g) 实现了乙醇最低售价为1.43 €/kg.
- 技术经济分析显示,对奶酪乳糖的经济影响 (门费或成本) 有很大的依赖.
结论:
- 政策的实施,特别是奶酪乳糖的门费,对乙醇的最低销售价格产生了积极的影响.
- 模拟过程可以作为现有乳制品或生物质加工设施的插件.
- 进一步的研究应该考虑将这一过程与现有基础设施相结合,以提高效率.
相关概念视频
01:29Microbes in Food Production
403
Microbial fermentation is central to food biotechnology, enhancing flavor, texture, preservation, and stability. Fermentative microorganisms metabolize carbohydrates into organic acids, alcohols, and other metabolites that inhibit spoilage organisms and improve digestibility while contributing distinctive sensory qualities.In baking, amylases naturally present in flour hydrolyze starch into monosaccharides such as glucose, which Saccharomyces cerevisiae ferments anaerobically. Through...
403
01:25Microbes in Beverage Production
298
Alcoholic beverages such as wine, beer, and spirits are the products of microbial fermentation processes that transform simple sugars into ethanol and a wide array of complex flavor compounds. These transformations rely on the metabolic activities of specific yeasts and bacteria, which are selected and controlled to yield the desired beverage characteristics.Wine Fermentation and MaturationWine production begins with the crushing of grapes to release juice and pulp, forming a must that is...
298
01:22Bioreactor Controls-III
67
Strain improvement is a foundational strategy in industrial microbiology aimed at maximizing microbial productivity, particularly because natural isolates typically yield commercially valuable products in very low concentrations. Although optimizing the culture medium and environmental conditions can improve yields, these adjustments are inherently limited by the organism’s genetic potential. As a result, the focus shifts toward genetic modifications to enhance biosynthetic capacity. The...
67
01:14Scale-Up Processes
105
The scale-up of microbial fermentation processes is essential in industrial biotechnology, allowing the transition from laboratory-scale experiments to commercial-scale production while aiming to maintain product yield and quality. This process requires meticulous adjustment of equipment design, process parameters, and contamination control strategies to accommodate increasing culture volumes.At the laboratory scale, cultures are typically maintained in 1 to 10-liter glass or autoclavable...
105
01:25Production of Organic Acids
105
Lactic acid, an important organic acid extensively applied in food, pharmaceutical, and biodegradable polymer industries, is primarily produced via microbial fermentation. This method is favored over chemical synthesis due to its environmental sustainability and capacity for enantiomerically pure product formation. Among various microbial processes, the fermentation of starch-based substrates stands out due to the abundance and renewability of raw materials like corn and potatoes.Hydrolysis of...
105
01:25Biofuels
107
The microbial conversion of organic matter into biofuels holds potential as a renewable energy source. Among biofuel sources, microalgae are recognized as a highly efficient and adaptable feedstock for biodiesel production, owing to their rapid biomass accumulation, elevated lipid productivity, and capacity to proliferate in diverse aquatic systems, including freshwater, marine, and wastewater habitats. Unlike terrestrial crops, microalgae do not compete for land and can achieve significantly...
107